K. Watanabe et al., STIMULATION OF CELL-GROWTH IN THE U-937 HUMAN MYELOID CELL-LINE BY HONEY ROYAL JELLY PROTEIN, Cytotechnology, 26(1), 1998, pp. 23-27
Royal jelly was fractionated by ion-exchange chromatography and a prot
ein (DIII protein) that had growth stimulating activity to the U-937 h
uman myeloid cell line was obtained. The molecular weight of the Dm pr
otein was 58 kDa on SDS-PAGE. The growth stimulating activity of the D
m protein was shown to be relatively heat and pH stable.