Vertebroplasty is an effective new radiologic procedure consisting of
the percutaneous injection of a biomaterial, usually methyl methacryla
te, into a lesion of a vertebral body, This technique allows marked or
complete pain relief and bone strengthening in most cases, The princi
pal indications for vertebroplasty are osteolytic metastasis and myelo
ma, painful or aggressive hemangioma, and osteoporotic vertebral colla
pse with debilitating pain that persists despite correct medical treat
ment, Radiography and computed tomography must be performed in the day
s preceding vertebroplasty to assess the extent of vertebral collapse,
the location and extent of the lytic process, the visibility and degr
ee of involvement of the pedicles, the presence of cortical destructio
n or fracture, and the presence of epidural or foraminal stenosis caus
ed by tumor extension or bone fragment retropulsion. Leakage of methyl
methacrylate during vertebroplasty may cause compression of adjacent
structures and necessitate emergency decompressive surgery; thus, the
procedure should be performed only in a surgical center. The decision
to perform vertebroplasty should be made by a multidisciplinary team b
ecause the choice between vertebroplasty, surgery, radiation therapy,
medical treatment, or a combination thereof depends on a number of fac
tors, Radiologists need to be aware of the various indications for ver
tebroplasty and of potential future developments and applications of t
he procedure.