SIMULTANEOUS DETERMINATION OF HALOACETIC ACIDS IN ENVIRONMENTAL WATERS USING ELECTROSPRAY-IONIZATION LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY

Negative ionization electrospray liquid chromatography mass spectromet ry was developed for the simultaneous determination of all nine haloac etic acids containing bromine and chlorine, Haloacetic acids were sepa rated on a crosslinked polystyrene resin column using 3% acetic acid d issolved in acetonitrile:water (20:80) as mobile phase. The precision of this method varied from +/-2.2 to +/-7.1% for nine haloacetic acids . In addition, quantitative results obtained with spiked water samples at three different concentrations are described. The Limit of detecti on of the proposed method using 200 mt of water samples was between 0. 003 and 0.070 mu g/L. This method was successfully applied to the trac e determination of haloacetic acids in waste water, river water, and s eawater.