A MURINE SPECIFIC SPLICING VARIANT OF THE ACETYLCHOLINE-RECEPTOR EPSILON-SUBUNIT GENE TRANSCRIPT

Authors
KOISHI K MCLENNAN IS
Citation
K. Koishi et Is. Mclennan, A MURINE SPECIFIC SPLICING VARIANT OF THE ACETYLCHOLINE-RECEPTOR EPSILON-SUBUNIT GENE TRANSCRIPT, Biochimica et biophysica acta. Molecular cell research, 1401(3), 1998, pp. 315-318
Citations number
10
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Molecular cell research → ACNP
ISSN journal
01674889
Volume
1401
Issue
3
Year of publication
1998
Pages
315 - 318
Database
ISI
SICI code
0167-4889(1998)1401:3<315:AMSSVO>2.0.ZU;2-F
Abstract
The acetylcholine receptor (AChR) is an ion channel involved in signal transmission from motorneuron to skeletal muscle. We describe here a murine-specific splicing variant of the epsilon subunit of the AChR (e psilon(s)), which lacks exon 5. epsilon(s) has a truncated extracellul ar domain which may affect the physiological characteristics of the re sulting AChR channel. (C) 1998 Elsevier Science B.V.