COMPUTER-ANALYSIS OF DNA-SEQUENCES

Computer-assisted analysis is an important instrument of DNA research. This review considers the methods of analysis of nucleotide sequences , describes the main algorithms, provides electronic addresses of the relevant e-mail and WWW servers, and suggests a tentative scheme for a nalysis of a newly sequenced DNA fragment. The review covers the probl ems of functional analysis (recognition of protein-coding regions and functional sites) and similarity search in the sequence databanks.