SUBCLINICAL ACTIVATION OF LUPUS NEPHRITIS BY RECOMBINANT HUMAN GROWTH-HORMONE

Authors
YAP HK LOKE KY MURUGASU B LEE BW
Citation
Hk. Yap et al., SUBCLINICAL ACTIVATION OF LUPUS NEPHRITIS BY RECOMBINANT HUMAN GROWTH-HORMONE, Pediatric nephrology, 12(2), 1998, pp. 133-135
Citations number
15
Categorie Soggetti
Pediatrics,"Urology & Nephrology
Journal title
Pediatric nephrology
ISSN journal
0931041X → ACNP
Volume
12
Issue
2
Year of publication
1998
Pages
133 - 135
Database
ISI
SICI code
0931-041X(1998)12:2<133:SAOLNB>2.0.ZU;2-6
Abstract
The effect of growth hormone (GH) on subclinical disease activity in a 15-year-old boy with previously quiescent lupus nephritis and chronic renal failure is described. Institution of supraphysiological doses o f GH resulted in a rise in erythrocyte sedimentation rate, decrease in serum complement, rise in anti-DNA antibody titers, and increase in T -cell activation markers, all of which improved following cessation of GH treatment.