SYNTHESIS AND REACTIVITY OF N-ALKYL-2-OXOALKANESULFONAMIDES

Authors
VEGA JA ALAJARIN R VAQUERO JJ ALVAREZBUILLA J
Citation
Ja. Vega et al., SYNTHESIS AND REACTIVITY OF N-ALKYL-2-OXOALKANESULFONAMIDES, Tetrahedron, 54(14), 1998, pp. 3589-3606
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
14
Year of publication
1998
Pages
3589 - 3606
Database
ISI
SICI code
0040-4020(1998)54:14<3589:SARON>2.0.ZU;2-N
Abstract
A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by r eacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reac tivity towards electrophiles was investigated in order to explore the regio-and stereoselectivity of the process. 2-Oxoalkanesulfonamides we re used to prepare 5-(methylsulfamoyl)-1,4-dihydropyridines derivative s. (C) 1998 Elsevier Science Ltd. All rights reserved.