RASMUSSEN ENCEPHALITIS - COMPLEMENTARY ROLE OF MULTITECHNIQUE NEUROIMAGING

Rasmussen encephalitis is a chronic, progressive inflammation of the b rain of unknown origin. Early diagnosis and treatment with immunoactiv e agents and/or hemispherectomy are sought to prevent the progressive cognitive decline that accompanies this disease. Combined anatomic and functional neuroimaging may serve to focus the diagnostic workup and to hasten brain biopsy for definitive diagnosis, Two biopsy proved cas es of Rasmussen encephalitis are presented. The importance of MR imagi ng, single-photon emission computed tomography, and proton MR spectros copy in the workup of this disease is discussed.