Sg. Kumagai et al., TREATMENT OF DIABETIC (NEUROPATHIC) FOOT ULCERS WITH 2-STAGE DEBRIDEMENT AND CLOSURE, Foot & ankle international, 19(3), 1998, pp. 160-165
We reviewed 33 patients with 37 wounds treated between November of 199
1 and December of 1995 in the Wound Care Center. A two-stage debrideme
nt and closure technique for neuropathic foot ulcers was performed. Pa
tients selected included those with obvious osteomyelitis and those wh
o had failed nonsurgical treatment. The approach included initial surg
ical excision of the ulcer with biopsy, bone resection with biopsy, an
d deep culture. The second-stage procedure 4 to 8 days later included
debridement of the wound and delayed closure. Intravenous antibiotic t
reatment using a central line was given postoperatively in patients wi
th documented osteomyelitis for at least 6 weeks and in patients with
infected soft tissues only for about 4 weeks. All patients remained no
nweightbearing for 4 weeks; this was felt necessary to prevent separat
ion of the wound edges. Four wounds in four patients failed to heal, a
nd two of these went on to amputation. Satisfactory healing occurred i
n 29 of 33 patients and in 33 of 37 wounds. The authors conclude that
two-stage surgical debridement and closure is an acceptable treatment
in selected nonhealing diabetic (neuropathic) foot ulcers.