LOCALIZATION OF THE CA2-BINDING S100A1 PROTEIN IN SLOW AND FAST SKELETAL-MUSCLES OF THE RAT()

Authors
MACO B BREZOVA A SCHAFER BW UHRIK B HEIZMANN CW
Citation
B. Maco et al., LOCALIZATION OF THE CA2-BINDING S100A1 PROTEIN IN SLOW AND FAST SKELETAL-MUSCLES OF THE RAT(), General physiology and biophysics, 16(4), 1997, pp. 373-377
Citations number
20
Journal title
General physiology and biophysics → ACNP
ISSN journal
02315882
Volume
16
Issue
4
Year of publication
1997
Pages
373 - 377
Database
ISI
SICI code
0231-5882(1997)16:4<373:LOTCSP>2.0.ZU;2-F
Abstract
The distribution of S100A1 in rat soleus and EDL muscles was studied i mmunocytochemically at the ultrastructural level using immunogold as m arker. Antigens were localized mainly in myofibrils at all levels of t he sarcomere. Immunogold particles along myofibrils were not uniformly distributed. The highest density of particles was found at Z-lines. A n increase in particle density was observed in the middle of half A-ba nds in EDL and in the middle of half I-bands in the soleus. Antigen si tes were also present at M-lines and at distinct. locations of the sar coplasmic reticulum.