CYTOTOXIC COUMARINS FROM THE AERIAL PARTS OF TORDYLIUM-APULUM AND THEIR EFFECTS ON A NON-SMALL-CELL BRONCHIAL-CARCINOMA LINE

Authors
KOFINAS C CHINOU I LOUKIS A HARVALA C ROUSSAKIS C MAILLARD M HOSTETTMANN K
Citation
C. Kofinas et al., CYTOTOXIC COUMARINS FROM THE AERIAL PARTS OF TORDYLIUM-APULUM AND THEIR EFFECTS ON A NON-SMALL-CELL BRONCHIAL-CARCINOMA LINE, Planta medica, 64(2), 1998, pp. 174-176
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences","Chemistry Medicinal
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
64
Issue
2
Year of publication
1998
Pages
174 - 176
Database
ISI
SICI code
0032-0943(1998)64:2<174:CCFTAP>2.0.ZU;2-J
Abstract
Seven coumarins were isolated from the aerial parts of Tordylium apulu m; their structures were established by spectroscopic means. All compo unds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asynchronous cells of the NSCLC-N6 line with a flow cytometry apparatus.