Two cases of regional odontodysplasia in girls are reported; one affec
ted the lower incisors, and the other the left maxilla. The first case
was radiographically followed over a 6-year period, during which time
the ghost teeth exhibited significant dentin formation, along with a
resultant decrease in pulp size and relative normalization of the radi
cular anatomy. nle second case involved the deciduous molars and the f
irst permanent molar. In addition to tooth alterations, both eases exh
ibited many odontogenic epithelial islands and extensive areas of calc
ification in the mucosa. Diagnosis, causes, and treatment are discusse
d in the light of recent data.