DISSEMINATED BURKITTS-LYMPHOMA AFTER KIDNEY-TRANSPLANTATION - A CASE-REPORT IN A BOY WITH DRASH SYNDROME

Purpose. We discuss the clinical, laboratory findings and treatment of a boy who developed Burkitt's lymphoma (BL) after renal transplant an d some issues about lymphoproliferative disorders after transplantatio n. Methods. A 6-year-old boy with Drash syndrome developed disseminate d Burkitt's lymphoma 38 months after transplantation for renal failure . Immunosuppressive therapy had consisted of prednisolone and cyclospo rine. Polychemotherapy was initiated. Results. Polychemotherapy induce d rapid and complete remission of the disease without major side effec ts despite the renal transplant allograft and prolonged immunosuppress ion. Conclusions. A child with posttransplantation B-cell high-grade l ymphoma can be successfully treated with the same chemotherapy regimen used for ordinary cases.