MEDICAL AND SURGICAL-TREATMENT OF OBSESSIVE-COMPULSIVE DISORDER

Citation
Jl. Rapoport et G. Inoffgermain, MEDICAL AND SURGICAL-TREATMENT OF OBSESSIVE-COMPULSIVE DISORDER, Neurologic clinics, 15(2), 1997, pp. 421
Citations number
41
Categorie Soggetti
Neurosciences,"Clinical Neurology
Journal title
ISSN journal
07338619
Volume
15
Issue
2
Year of publication
1997
Database
ISI
SICI code
0733-8619(1997)15:2<421:MASOOD>2.0.ZU;2-T
Abstract
Current treatment outcomes for obsessive-compulsive disorder patients are far better than in past decades, but variability in treatment resp onse remains. Most obsessive-compulsive disorder patients, but not all , respond to antidepressant agents with prominent serotonin uptake blo cking properties. Because clomipramine's usefulness is limited by side effects which often accompany its use, a considerable degree of atten tion has shifted to selective serotonin reuptake inhibitors. A number of studies have also provided evidence for the effectiveness of medica tion other than those mainly involving serotonergic function, either a s augmenting agents or for comorbid disorders. Neurosurgery may be use ful for highly selected subjects.