MULTIPLE-SCLEROSIS - WHAT HAVE WE LEARNED FROM MAGNETIC-RESONANCE-IMAGING STUDIES

We review studies that have examined the relationship between magnetic resonance imaging findings and clinical disability, postmortem observ ations, and cognitive dysfunction in patients with multiple sclerosis. We also review the use of magnetic resonance imaging findings as an o utcome measure in clinical trials assessing the efficacy of new therap eutic agents for the treatment of multiple sclerosis. More advanced ap plications of magnetic resonance imaging and their use in multiple scl erosis is addressed later in the article.