M. Raucoulesaime et D. Grimaud, MANAGEMENT OF HIGH-RISK PATIENTS IN THE P ERIOPERATIVE PERIOD - DIABETIC-PATIENTS, La Presse medicale, 27(9), 1998, pp. 444-451
Preoperative care: The preoperative consultation is particularly impor
tant in patients with diabetes mellitus due to the frequency and varie
ty of degenerative complications. Cardiovascular disorders are the mai
n cause of mortality, usually related to coronary artery disease, hype
rtension, left ventricular dysfunction and impaired regulatory functio
ns caused by damage to sympathetic and parasympathetic cardiac innerva
tion. Diabetic dysautonomic neuropathy: Sudden cardiac arrest, rhythm
disorders and unstable blood pressure during the operative period are
well-known complications of diabetic dysautonomic neuropathy, increasi
ng the risk of operative morbidity and mortality in diabetics. The dia
gnosis is established with systolic blood pressure and heart rate, dia
stolic blood pressure using the grip test respiratory arrhythmia, and
the Valsalva manoeuvre. In addition, the cervical spine in diabetics i
s stiffened by abnomal collagen structure, explaining the ten-fold inc
rease in intubation difficulties. Gastroparesia, suggested by clinical
signs, increases the risk of regurgitation and requires specific prev
entive measures. Finally the neurology examination may reveal sensorom
otor disorders which are particularly important because nervous lesion
s may be exacerbated during the postoperative period. Choice of an ane
sthesic: The major drawback of general anesthesia is that it masks sig
ns of hypoglycemia. Spinal anesthesia is contraindicated in case of dy
sautonomic neuropathy. Glucose control: Controlled insulin and glucose
infusion in the perioperative period can avoid the risk of hyperosmol
arity or ketoacidosis.