CARCINOSARCOMA OF THE COLON - REPORT OF A CASE AND REVIEW OF THE LITERATURE

We report a case of carcinosarcoma in the transverse colon in a 60-yea r-old woman, She was admitted to our hospital for further examination of occult blood in October, 1995. Colonoscopy disclosed an elevated le sion with ulceration in the transverse colon, and she underwent right hemicolectomy. Histopathological examination revealed the tumor to con sist of both carcinomatous and sarcomatous elements, the latter being more predominant, Immunohistochemistry revealed vimentin immunoreactiv ity in most of the sarcomatous cells, and S-100 and myoglobin in a few carcinomatous cells, Distinct carcinomatous features were noted in on e superficial portion of the tumor, and these carcinomatous cells show ed immunoreactivity for epithelial membrane antigen. The patient is al ive 14 months after surgery without evidence of recurrence, To our kno wledge, this is the fourth reported case of carcinosarcoma of the colo n, Our review of the literature disclosed poor prognosis in colonic ca rcinosarcoma.