RISING LEVELS OF HUMAN CYTOMEGALOVIRUS (HCMV) ANTIGENEMIA DURING INITIAL ANTIVIRAL TREATMENT OF SOLID-ORGAN TRANSPLANT RECIPIENTS WITH PRIMARY HCMV INFECTION

Authors
GERNA G ZAVATTONI M PERCIVALLE E GROSSI P TORSELLINI M REVELLO MG
Citation
G. Gerna et al., RISING LEVELS OF HUMAN CYTOMEGALOVIRUS (HCMV) ANTIGENEMIA DURING INITIAL ANTIVIRAL TREATMENT OF SOLID-ORGAN TRANSPLANT RECIPIENTS WITH PRIMARY HCMV INFECTION, Journal of clinical microbiology, 36(4), 1998, pp. 1113-1116
Citations number
17
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
36
Issue
4
Year of publication
1998
Pages
1113 - 1116
Database
ISI
SICI code
0095-1137(1998)36:4<1113:RLOHC(>2.0.ZU;2-Z
Abstract
In 7 of 18 solid-organ transplant recipients with primary human cytome galovirus (HCMV) infection, HCMV antigenemia levels were unexpectedly found to rise significantly (P = 0.018) during a mean time of 7.3 +/- 3.2 days after initiation of specific antiviral treatment, whereas cor responding levels of viremia dropped significantly (P = 0.043). Thus, shifting to an alternative antiviral drug based solely on increasing a ntigenemia levels is not justified in this group of patients.