Pl. Jooste et al., IODINE DEFICIENCY AND ENDEMIC GOITER IN THE LANGKLOOF AREA OF SOUTH-AFRICA, South African medical journal, 87(10), 1997, pp. 1374-1379
Objective. To quantify the prevalence of iodine deficiency and endemic
goitre in the Langkloof area. Design. A cross-sectional study. Settin
g. Four primary schools in four communities in the Langkloof, Subjects
. 565 primary schoolchildren from Standard 2 to Standard 5. Outcome me
asures. Clinical diagnosis of thyroid size by palpation, level of iodi
ne in urine and drinking water samples, level of iodine in iodised sal
t samples from the area, percentage of households with iodised salt on
the premises, and anthropometric measures of body height and weight.
Results. The prevalence of endemic goitre varied from 14.3% to 30.2% i
n the four communities and, based on urinary iodine levels, the iodine
deficiency ranged from mild to severe. Both iodised and non-iodised s
alt were available at the local grocery stores but only small percenta
ges of households had iodised salt in the house. The iodine content of
drinking water was low. Anthropometric indices of undernutrition indi
cated medium to high levels of stunting in three of the four communiti
es, the worst being in the community with the highest goitre prevalenc
e. Conclusions. Endemic goitre caused by iodine deficiency is a public
health problem in the Langkloof, varying in severity from mild to sev
ere in the different communities. The impact of mandatory iodisation o
f table salt, introduced at the end of 1995, needs to be assessed in t
hese communities.