Nw. Wilson et al., LARYNGEAL PAPILLOMA PRESENTING AS STEROID-DEPENDENT ASTHMA IN A 3-YEAR-OLD CHILD WITHOUT RECURRENT STRIDOR, ALLERGY AND ASTHMA PROCEEDINGS, 19(1), 1998, pp. 11-13
Upper airway obstruction is well described as a cause of apparent asth
ma. However, it can be very difficult to diagnose in young children. T
his 3-year-old male presented with a 1-year history of severe recurren
t wheezing with six emergency room visits in the previous 5 months. Cr
omolyn, inhaled corticosteroids, and frequent predinisolone bursts had
not controlled the wheezing. There was no history of barky cough, cro
up, or strider. His physical examination was notable for marked nasal
obstruction. Ar initial presentation, his lungs were normal with no wh
eezing or strider. Soft tissue neck X-ray films suggested the presence
of a subglottic mass. A large solitary papilloma was found on broncho
scopy. After surgical removal, there was no further wheezing noted by
either the parents or his physicians. Laryngeal papillomatosis may mim
ic asthma in the absence of symptoms of hoarseness, croup, or strider
It should be particularly considered in 2 to 4-year-old children with
recurrent wheezing that is poorly responsive to aggressive therapy inc
luding oral corticosteroids.