THE BIOLOGY OF ESTROGEN-MEDIATED REPAIR OF CARDIOVASCULAR INJURY

Citation
Ch. Selzman et al., THE BIOLOGY OF ESTROGEN-MEDIATED REPAIR OF CARDIOVASCULAR INJURY, The Annals of thoracic surgery, 65(3), 1998, pp. 868-874
Citations number
56
Categorie Soggetti
Surgery,"Cardiac & Cardiovascular System","Respiratory System
ISSN journal
00034975
Volume
65
Issue
3
Year of publication
1998
Pages
868 - 874
Database
ISI
SICI code
0003-4975(1998)65:3<868:TBOERO>2.0.ZU;2-V
Abstract
Women appear to be protected from cardiovascular disease until the ons et of menopause. Considerable evidence supports the atheroprotective e ffects of endogenous and supplemental estrogens. The beneficial effect s of estrogens on lipid metabolism cannot wholly explain this phenomen on. Accumulating data suggest that estrogen may act at the cellular an d molecular level to influence atherogenesis. The purpose of this revi ew is to examine lipid-independent mechanisms of estrogen-mediated ath eroprotection after cardiovascular injury. (C) 1998 by The Society of Thoracic Surgeons.