The management of acute pancreatitis commences with confirming the dia
gnosis and establishing the aetiology. Improved methods of assessing t
he biliary tree may reduce the number of patients regarded as having i
diopathic pancreatitis. Detailed clinical and laboratory protocols, de
signed to assess severity, have no major advantage over clinical asses
sment. The contrast-enhanced computed tomography scan is important to
assess the degree of pancreatic necrosis and to detect local complicat
ions. The treatment of pancreatitis continues to be largely supportive
. However, controlled studies support the use of antibiotics in severe
acute pancreatitis and indicate a possible role for the use of octreo
tide and antioxidants. The place of endoscopic and surgical interventi
on is becoming better defined. Once an attack has passed, further inve
stigation is often required in a bid to prevent further episodes of in
flammation.