THE WAVE-GUIDE MACH-ZENDER INTERFEROMETER AS ATRAZINE SENSOR

Immunoanalytical techniques used in combination with a highly sensitiv e Mach-Zender waveguide sensor give a device that is capable of fast o n-line monitoring of immunoreactions. The on-line monitoring is especi ally attractive when the sensor can be used as an environmental probe. It is demonstrated that low concentrations of atrazine can be measure d with a sensitivity around the EC limit of 100 ng/L. These measuremen ts are performed with an inhibition technique. In combination with ''a dynamic slope method'' one complete measurement is done within 10 min . Sensor measurements show the same sensitivity and errors as parallel ELISAs.