STRESS, HEADACHE, AND PHYSIOLOGICAL DISREGULATION - A TIME-SERIES ANALYSIS OF STRESS IN THE LABORATORY

This study examined the stress-headache relationship from a disregulat ion framework by monitoring both physiological responses (eg, pulse, b lood volume, skin resistance, and EMG) and self-reported responses to a stressful event in tension and migraine headache sufferers, as well as in headache-free controls. Responses were analyzed via time-series analyses to determine whether self-reports of stress were correlated w ith physiological measures of stress. It was hypothesized that tension and migraine headache sufferers would show fewer significant correlat ions than control participants between their self-reports of stress an d physiological activity. Data analyses supported this hypothesis for tension headache sufferers, but generally not for migraine headache su fferers. The most compelling support for the hypothesis in tension hea dache sufferers came from the cross-correlations between self-reported stress and pulse rate.