BACKGROUND AND OBJECTIVES: To determine the frequency of scar tissue f
ormation requiring surgical intervention after single-plate Molteno im
plantation and the outcome of excision of the encapsulated bleb. PATIE
NTS AND METHODS: A retrospective study was performed on 95 eyes of 73
consecutive patients who underwent a single-stage Molteno implantation
for refractory glaucoma. Fourteen eyes of 12 patients developed an en
capsulated bleb. A successful outcome after bleb excision was defined
as final intraocular pressure (IOP) between 6 and 22 mm Hg with the sa
me amount of medication as preoperatively or less. RESULTS: At the end
of the mean follow-up of 30 months (range 8 to 75), the mean IOP (19.
7+/-3.5 mm Hg) after bleb excision was significantly lower than the pr
eoperative IOP (35.2+/-10.1 mm Hg; P<.001). The overall conventional s
uccess rate was 75%. CONCLUSION: Excision of the encapsulated Molteno
bleb offers an alternative in severely damaged eyes that have undergon
e several surgical procedures.