To evaluate the clinical usefulness and limitations of three-dimension
al (3-D) imaging of laryngeal cancers by high-speed helical (spiral) C
T scanning, 3-D images were reconstructed for one dissected human lary
nx and 10 patients with laryngeal cancer. The larynges were scanned in
1- to 2-mm slices, and were reconstructed using a slice thickness of
0.5-1.0 mm. The macroscopic (or endoscopic) findings and the 3-D CT im
ages of the larynx were compared. The selected threshold CT values wer
e -600 HU (Hounsfield units) to -100 HU for the mucous membranes, and
250 HU for bone. Under these conditions, almost all of the structures
remained distinct. The 3-D images of the larynx obtained by helical CT
were very helpful in understanding laryngeal anatomy, especially in t
he subglottic area, which cannot be seen clearly by endoscopy or conve
ntional axial CT. Clinically, this system would have advantages in the
detection of subglottic cancers, or the invasion of glottic or suprag
lottic cancers into the subglottic area.