A series of studies investigated occupational exposure to pesticides a
mong fruit growers in The Netherlands during spraying and reentry of o
rchards between 1990 and 1992 to identify and quantify determinants of
exposure. Determinants of exposure are discussed as a starting point
for hazard identification and control. Captan was used as a marker for
exposure. Cabin use on the tractor was the most prominent determinant
of derma[ exposure during spraying. For respiratory exposure, factors
related to preparation of pesticides were most prominent. A long dura
tion of exposure may reflect a different exposure situation compared w
ith a short duration of exposure. As different determinants of exposur
e prevailed for each subgroup, consideration should be given to constr
ucting exposure models for each group separately. Dislodgeable foliar
residue (DFR) was the most prominent determinant of exposure for both
respiratory and dermal exposure during reentry. However, no significan
t relation between DFR and dermal exposure of forehead and sternal are
a was found, perhaps because there was no direct contact-with foliage
here. Therefore, use of a transfer factor based on DFR to estimate tot
al dermal exposure is only a crude estimate. The half-life of captan o
n crops varied from 10-17 days, so substantial exposure when entering
the orchard is very likely, particularly when spraying frequency is hi
gh. The main starting points for reduction of exposure are use of a ca
bin, DFR, and individual time spent on different tasks. Determinants t
hat are constant over time (cabin use) may have an especially great in
fluence on grouping workers, according to long-term exposure in epidem
iological studies. As determinants of exposure vary for the different
exposure routes and body locations (for dermal exposure), the measure
of interest for a specific study design will decide which determinants
are most relevant.