Galactography is useful in the evaluation of spontaneous discharge fro
m the nipple of a nonlactating breast. Without galactography, surgeons
have relied on either masectomy or excision of the major duct system
responsible for the discharge. From January 1989 to May 1996, 106 gala
ctograms were performed with monofilament polypropylene suture guiding
for duct cannulation in 105 cases. The discharge duct was identified
by pre-operative galactography, followed by a selective excision of du
ctal-lobular unit. In all tissue specimens, the cause of the pathologi
c secretion was found histologically; most often, it was intraductal p
apilloma (42.6%). in 35.6% of the specimens, findings with a prospecti
ve significance (papillomatosis, hyperplasia, carcinoma) were discover
ed and further operative treatment was initiated. The color of the dis
charge allowed no prediction of the histological findings. The accurac
y of galactography was 88.4%, 84.6%, and 77.4% in papilloma, cancer, a
nd other benign lesions, respectively It is better than physical exami
nation and other tests. Galactography represents a useful test in the
diagnostic workup of secretory breasts. (C) Elsevier Science Inc., 199
8.