An. Shetty et al., 3D BREATH-HOLD CONTRAST-ENHANCED MRA - A PRELIMINARY EXPERIENCE IN AORTA AND ILIAC VASCULAR-DISEASE, Journal of computer assisted tomography, 22(2), 1998, pp. 179-185
Purpose: Our goal was to describe a 3D breath-hold (3D BH) contrast-en
hanced MRA technique and apply the technique to patients with known or
suspected aortic and iliac artery disease. Method: A fat-suppressed 3
D GRE pulse sequence was designed with a total of 16 partition encodin
gs. This took <24 s for data acquisition in the abdomen and pelvis and
was easily achieved during a single breath-hold. The technique was ap
plied to 26 patients who presented with either known or suspected abdo
minal aortic or iliac vascular diseases. For comparison, in 19 patient
s a 2D TOF MRA pulse sequence with a traveling saturation band was use
d. Angiographic correlation was made in 18 studies. Results: The 3D BH
MRA was easily applicable in the evaluation of vascular anatomy and p
athology. In three cases, it was superior to 2D TOF and conventional a
ngiography for visualizing clot within the wall of an aneurysm in the
abdominal aorta. In 20 cases, both MRA techniques overestimated the de
gree of stenosis in the lower peripheral vessels; however, this was mo
re pronounced on 2D TOF. In five cases, the aneurysm wall was clearly
defined by 3D BH MRA, whereas there was considerable signal loss in 2D
TOF due to complex flow. With 3D BH MRA, the entire vessel territory
both in abdominal aorta and in iliac vessels was visualized in all cas
es without signal falloff in the FOV. Breath-holding provided static i
mages of the vessels that were free of blurring due to respiratory mot
ion. Conclusion: Preliminary experience suggests that 3D BH with its d
istinct advantage of speed may serve as a useful screening tool for pa
tients who cannot have conventional angiography or tolerate a lengthy
MR examination of the abdominal aorta and iliac arteries.