POLYCYSTIC LIVER-DISEASE, INDICATION FOR LIVER-TRANSPLANTATION OR DECOMPRESSIVE LIVER RESECTION

In patients suffering from polycystic liver disease sclerosing therapy , decompressive hepatic resection and liver transplantation represent the main therapeutic options. Since 1987 10 females with highly sympto matic polycystic liver disease underwent hepatic resection for decompr ession (five left lateral bisegmentectomies, one left hemihepatectomy, one right central and three bilateral atypical resections). Despite o f a 0 % lethality 3 patients developed complications, in two cases an abscess had to be drained and in one case a postoperatively increasing hepatic insufficiency required urgent liver transplantation. Patient' s symptoms were remarkably improved in 8 cases, but only 6 patients ha d a long lasting benefit over years. One patient was resected a second time three years after the first operation and is free of symptoms fo r another five years. 6/96 the ''European Liver Transplant Registry'' has listed 81 patients after liver transplantation because of polycyst ic liver disease. 5-year survival is 78,2 %. So liver transplantation offers a therapeutic alternative for patients severely suffering from symptoms or increasing hepatic insufficiency.