CORRELATION BETWEEN BIOEFFECTOR CHARACTERISTICS OF SPHINGOLIPIDS AND THE STRUCTURE OF THEIR HYDROPHOBIC FRAGMENT

Authors
DYATLOVITSKAYA EV
Citation
Ev. Dyatlovitskaya, CORRELATION BETWEEN BIOEFFECTOR CHARACTERISTICS OF SPHINGOLIPIDS AND THE STRUCTURE OF THEIR HYDROPHOBIC FRAGMENT, Biochemistry, 63(1), 1998, pp. 55-61
Citations number
78
Categorie Soggetti
Biology
Journal title
Biochemistry → ACNP
ISSN journal
00062979
Volume
63
Issue
1
Year of publication
1998
Pages
55 - 61
Database
ISI
SICI code
0006-2979(1998)63:1<55:CBBCOS>2.0.ZU;2-5
Abstract
The effect of the structure of the hydrocarbon sphingoid base chain (l ength, presence of double bonds, and steric configuration of functiona l groups) and the length of the fatty acid residue of a ceramide molec ule on the bioregulatory activities of sphingoids and ceramides is rev iewed. Particular emphasis is placed on the role of functional groups (OH- and NH2-) typical of the sphingoid chain.