NUCLEOSIDES AND NUCLEOTIDES - 165 - CHEMICAL LIGATION OF OLIGODEOXYNUCLEOTIDES HAVING A MERCAPTO GROUP AT THE 5-POSITION OF 2'-DEOXYURIDINEVIA A DISULFIDE BOND

Authors
UENO Y NAKAGAWA A MATSUDA A
Citation
Y. Ueno et al., NUCLEOSIDES AND NUCLEOTIDES - 165 - CHEMICAL LIGATION OF OLIGODEOXYNUCLEOTIDES HAVING A MERCAPTO GROUP AT THE 5-POSITION OF 2'-DEOXYURIDINEVIA A DISULFIDE BOND, Nucleosides & nucleotides, 17(1-3), 1998, pp. 283-289
Citations number
24
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
17
Issue
1-3
Year of publication
1998
Pages
283 - 289
Database
ISI
SICI code
0732-8311(1998)17:1-3<283:NAN-1->2.0.ZU;2-H
Abstract
We describe the nonenzymatic ligation of oligodeoxynucleotides (ODNs) containing a mercapto group at the 5 position of 2'-deoxyuridine via a disulfide bond. Two ODNs containing different sequences were efficien tly ligated in the presence of a template by this method.