Eb. Blanchard et al., POSTTRAUMATIC-STRESS-DISORDER AND COMORBID MAJOR DEPRESSION - IS THE CORRELATION AN ILLUSION, Journal of anxiety disorders, 12(1), 1998, pp. 21-37
We have examined data from 107 motor-vehicle accident (MVA) victims wi
th regard to whether the presence of comorbid depression is important
clinically, and with regard to whether the threshold for diagnosing th
e comorbid depression should be raised because of symptom overlap betw
een posttraumatic stress disorder (PTSD) and major depression. Of the
62 MVA victims who met the criteria for PTSD 1 to 4 months post-MVA, 3
3 also met the criteria for major depression, with 27 cases for which
the depression occurred post-MVA. A LISREL 8.12a analysis indicates th
at PTSD and major depression are correlated, but independent, response
s to trauma. Those with PTSD and depression are more subjectively dist
ressed, suffer more major role impairment, and remit less readily over
the first 6 months of prospective follow-up than those with PTSD alon
e. The threshold for diagnosing comorbid depression (5 or 6 depressive
symptoms versus 7 to 9 depressive symptoms) has no important effects
on any of the indicators of ''caseness.'' (C) 1998 Elsevier Science Lt
d.