N. Akimoto et al., BIOCOMPATIBILITY OF CLEARFIL LINER BOND-2 AND CLEARFIL AP-X SYSTEM ONNONEXPOSED AND EXPOSED PRIMATE TEETH, Quintessence international, 29(3), 1998, pp. 177-188
Objective: Recent studies have demonstrated that acid etching of vital
dentin and pulpal tissue does not retard pulpal healing, odontoblasto
id cell differentiation, or dentinal bridge formation when the pulp is
capped with adhesive resins. The purpose of this study was to evaluat
e the pulpal response in nonexposed and exposed monkey pulps to treatm
ent with the Clearfil Liner Bond 2 and Clearfil AP-X system. Method an
d materials: Class V and Class I cavities in nonexposed and exposed pu
lps were observed at 7 or 8, 27, and 97 days. Results: There were no d
ifferences in pulpal inflammation between the Clearfil Liner Bond 2/Cl
earfil AP-X specimens and calcium hydroxide controls in either Class V
or Class I cavities at the various time periods. Conclusion: Clearfil
Liner Bond 2 and Clearfil AP-X system is not toxic to either nonexpos
ed or exposed pulpal tissues when placed according to manufacturer's d
irections.