MULTIFOCAL ELECTRORETINOGRAPHY IN MACULAR DISEASES

Background Multifocal electroretinography allows physiological mapping of the central retina. The purpose of this study was to describe the spatial distribution of ERG-activity in patients with impairment of ma cular function which usually do not exhibit a pathologic Ganzfeld-ERG. Subjects and methods 6 patients with macular lesions due to uveitis ( 4), retinitis centralis serosa (1), and contusio bulbi (1) were examin ed using the multifocal ERG technique. Results In normal volunteers th e response density of the multifocal ERG decreased with eccentricity a ccording to cone density distribution. In eyes with impaired central v ision the foveal and macular responses were markedly diminished while surrounding signals were of normal or moderately decreased amplitudes. Conclusions With the multifocal ERG disturbances of macular function due to oedema and secondary structural changes were detected in the pr esented cases and the extension of the central lesions was estimated.