Although a number of devices have been developed to monitor sleep and
breathing in the home, there are few publications on methodologies by
which CPAP can be titrated in the home setting. This study was conduct
ed to determine the outcome of CPAP titration in the home using the He
althdyne NightWatch (NW) system. This home sleep-evaluation system was
used to diagnose sleep apnea in 30 patients using a previously descri
bed methodology. These patients subsequently underwent CPAP titration
in the home using the NW system, with modem technology allowing the tr
ansfer of data from the home to the laboratory. This group was compare
d with 30 patients who were diagnosed with sleep apnea using standard
in-lab polysomnography and had CPAP titrated on a full night in the la
boratory. Both groups were subsequently placed on CPAP at the appropri
ate pressure for 6-8 weeks, after which a full in-lab study was comple
ted to assess CPAP efficacy at the prescribed pressure. Compliance was
also determined using a pressure-activated monitor. No differences in
any variable assessed could be found between the two groups. Mean com
pliance was 4.6+0.5 (SEM) and 4.3+0.5 hours of CPAP use per night for
the home and in-lab groups respectively. Mean AHIs on the follow-up st
udy were 7.4+1.2 and 7.6+1.6 events per hour for the home versus in-la
b groups. Sleep stage distribution was also quite comparable between g
roups. As a result, this study suggests that sleep apnea can be diagno
sed and CPAP titrated in the home with a similar outcome, at least at
6 to 8 weeks, to standard in-laboratory testing.