THE PROPER BINORMAL MODEL - PARAMETRIC RECEIVER OPERATING CHARACTERISTIC CURVE ESTIMATION WITH DEGENERATE DATA

Rationale and Objectives. The authors assessed the use of a ''proper'' binormal model and a new algorithm for maximum-likelihood estimation of receiver operating characteristic (ROC) curves from degenerate data . Methods. The proper binormal ROC model uses as its decision variable a monotonic transformation of the likelihood ratio that is associated with a pair of normal distributions, thereby ensuring fitted ROC curv es with monotonic slope but maintaining a relationship with the conven tional binormal model. A computer program entitled PROPROC was used to fit proper ROC curves to data obtained from computer-simulated and re al observer studies. Results. ROC indexes such as total area were esti mated with PROPROC and compared with the corresponding values obtained from the conventional procedures. Conclusion. The proper binormal ROC model overcomes the problem of degeneracy in ROC curve fitting. PROPR OC is highly robust and yields ROC estimates with less bias and greate r precision than those obtained with the conventional binormal model.