Y. Murai et al., MAGNETIC-RESONANCE IMAGING-DOCUMENTED EXTRAVASATION AS AN INDICATOR OF ACUTE HYPERTENSIVE INTRACEREBRAL HEMORRHAGE, Journal of neurosurgery, 88(4), 1998, pp. 650-655
Object. The aim of this study was to determine the usefulness of magne
tic resonance (MR) imaging-documented extravasation as an indicator of
continued hemorrhage in patients with acute hypertensive intracerebra
l hemorrhage (ICH). Methods. The authors studied 108 patients with acu
te hyperintensive ICH. Imaging modalities included noncontrast-enhance
d computerized tomography (CT) scanning, gadolinium-enhanced MR imagin
g, and conventional cerebral angiography obtained within 6 hours after
the onset of hemorrhage. A repeated CT scan was obtained within 48 ho
urs to evaluate enlargement of the hematoma. Findings on MR imaging in
dicating extravasation, including any high-intensity signals on T-1-we
ighted postcontrast images, were observed in 39 patients, and 17 of th
ese also showed evidence of extravasation on cerebral angiography. The
presence of extravasation on MR imaging was closely correlated with e
vidence of hematoma enlargement on follow-up CT scans (p < 0.001). Con
clusions. Evidence of extravasation documented on MR imaging indicates
persistent hemorrhage and correlates with enlargement of the hematoma
.