Objective: To assess the risk of probe contamination following transva
ginal ultrasonography. Design: Prospective cohort study. Setting: Univ
ersity Infertility Center. Patient(s): Women undergoing transvaginal u
ltrasonography. Intervention(s): One physician obtained 840 consecutiv
e transvaginal ultrasonograms over nine months. Latex condoms were use
d to cover the probe. Following examination, the condoms were removed
and the probe was wiped with a germicidal disposable cloth and left to
air dry for 5 minutes. Condoms were filled with water and examined fo
r leaks. Main Outcome Measure(s): Number of perforations and distance
from condom tip. Result(s): Seventeen (2%) of 840 condoms leaked. The
mean distance from the tip to the point of leakage was 10.6 cm +/- 2.8
(mean +/- SD; range, 7-14). Sixty-five percent of the leaks were less
than or equal to 10 cm from the tip. In several instances, two leakin
g condoms were found within a few examinations of each other. No visua
l contamination of the probe was noted. Conclusion(s): Although only 2
% of condoms leaked, 65% were at distances that could have led to prob
e soiling intravaginally. While no body fluids were grossly visible, m
icroscopic contamination was still possible. Since perforations were n
oted in close, and even consecutive scans, this study underscores the
need for routine probe disinfection between examinations. (C) 1998 by
American Society for Reproductive Medicine.