MATRIX METALLOPROTEINASE INHIBITORS 1998

Authors
BECKETT RP WHITTAKER M
Citation
Rp. Beckett et M. Whittaker, MATRIX METALLOPROTEINASE INHIBITORS 1998, Expert opinion on therapeutic patents, 8(3), 1998, pp. 259-282
Citations number
82
Categorie Soggetti
Medicine, Legal","Pharmacology & Pharmacy
Journal title
Expert opinion on therapeutic patents → ACNP
ISSN journal
13543776
Volume
8
Issue
3
Year of publication
1998
Pages
259 - 282
Database
ISI
SICI code
1354-3776(1998)8:3<259:MMI1>2.0.ZU;2-M
Abstract
Inhibition of matrix metalloproteinases (MMPs) as an approach to treat ment of diseases such as cancer, arthritis and multiple sclerosis (MS) is now an area of intense interest within the pharmaceutical industry . This review summarises developments in the design and clinical evalu ation of synthetic MMP inhibitors since the subject was last covered i n this journal in 1996.