Duplications of the gastrointestinal tract are exceedingly rare in lab
oratory animals. We report a case of a communicating intestinal duplic
ation in a 17-wk-old Sprague-Dawley (SD) rat. The duplication was pres
ent in the mesenteric border of the ileum, and both proximal and dista
l ends were communicated with the lumen of ileum. Histologically, the
duplicated portion had a thick muscle wall and a mucosa similar to tha
t of the small intestine. This is the first reported case of intestina
l duplication in an SD rat.