LIPOBLASTOMA - A CASE WITH T(7-8)(Q31-Q13)

Authors
PANARELLO C ROSANDA C MORERIO C RUSSO I DALLORSO S GAMBINI C RICCO AS STORLAZZI T ARCHIDIACONO N ROCCHI M
Citation
C. Panarello et al., LIPOBLASTOMA - A CASE WITH T(7-8)(Q31-Q13), Cancer genetics and cytogenetics, 102(1), 1998, pp. 12-14
Citations number
14
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
102
Issue
1
Year of publication
1998
Pages
12 - 14
Database
ISI
SICI code
0165-4608(1998)102:1<12:L-ACWT>2.0.ZU;2-9
Abstract
Lipoblastoma is a rare benign adipose tumor which, in all of the cases so far described, presents an involvement of chromosome 8 in the regi on 8q11-23. We hereby report the results of the second case of lipobla stoma studied by fluorescence in situ hybridization (FISH), in a 13-mo nth-old boy. An abnormal karyotype 46,XY,t(7;8)(q31;q13) was found in 90% of the metaphases examined, in agreement with the previously repor ted observations. We suggest the region 8q11-23 may contain a relevant locus for lipoblastoma origin. (C) Elsevier Science Inc., 1998.