A NEW PREPARATION OF ESTERS FROM CARBONYL-COMPOUNDS FOLLOWING LITHIUMALUMINUM-HYDRIDE REDUCTION

Authors
GUO ZM SINDELAR RD
Citation
Zm. Guo et Rd. Sindelar, A NEW PREPARATION OF ESTERS FROM CARBONYL-COMPOUNDS FOLLOWING LITHIUMALUMINUM-HYDRIDE REDUCTION, Synthetic communications, 28(6), 1998, pp. 1031-1039
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
28
Issue
6
Year of publication
1998
Pages
1031 - 1039
Database
ISI
SICI code
0039-7911(1998)28:6<1031:ANPOEF>2.0.ZU;2-1
Abstract
A modified work-up procedure for the Lithium aluminum hydride (LiAlH4) reduction of esters and other carbonyl compounds is described. The on e pot procedure converts an ester to its ''homo-reverse ester'' and ot her carbonyl compounds to esters. The key step is trapping the resulti ng intermediate aluminum alkoxide during reflux with an ester.