G. Berube et M. Lepage, UNEXPECTED TRANSESTERIFICATION OF N-(TRIFLUOROACETYL) DOXORUBICIN WITH ACETYLSALICYLIC-ACID - FORMATION OF 4'-O-ACETYL-N-(TRIFLUOROACETYL) DOXORUBICIN, Synthetic communications, 28(6), 1998, pp. 1109-1116
Three new N-(trifluoroacetyl) doxorubicin analogues have been synthesi
zed under mild reaction conditions. An unexpected transesterification
reaction was observed when N-(trifluoroacetyl) doxorubicin was treated
with acetylsalicylic acid under the same conditions.