INFLUENCE OF CEREBROLYSIN ON THE OXIDANT HOMEOSTASIS, CONTENT OF MICROELEMENTS AND ELECTROLYTES IN CHILDREN WITH MINIMAL CEREBRAL-DYSFUNCTION

In 36 children of 3-8 years old with minimal cerebral dysfunction ther e were evaluated both concentrations of malonic dyaldehyde in blood pl asma, erythrocytes and platelets as well as the content of 25 elements (K, Mg, Ca, Na, P, Se, Zn, Co, Cr, Cu, Fe, Mn, Mo, Si, Li, Ni, V, Pb, Sn, Cd, Al, As, Be, Bi, Ti) in hairs. These indices were estimated bo th before and after course of cerebrolysin therapy (the a dose 2-5 ml intramuscularly during 1 month). There was observed positive influence of the drug on the clinical manifestations of the disease, oxidant an d elements homeostasis. Nuclear-emission analysis of the elements' com position of cerebrolysin revealed quite high content in the drug of ma gnesium, potassium, phosphorus and selenium which had neuroactive and antioxidant properties.