M. Ohji et al., SULFUR-HEXAFLUORIDE AND PERFLUOROPROPANE DO NOT ESCAPE FROM A PLASTICSYRINGE CLOSED WITH A STOPCOCK, American journal of ophthalmology, 123(5), 1997, pp. 709-711
PURPOSE: To evaluate during various intervals of time the escape of lo
ng-acting gases contained in a plastic syringe closed with a stopcock
or a plastic cap. METHODS: A 60-ml plastic syringe was filled or parti
ally filled with a long acting gas, either sulfur hexafluoride or perf
luoropropane. The tip of the syringe was closed with either a stopcock
or the syringe's plastic cap. After various intervals of time, the co
ncentration of the long acting gas in the syringe was measured by gas
chromatography. RESULTS: The concentration of both long acting gases w
as higher than 98% at 24 hours after filling when the syringe was clos
ed with a stopcock; however, it was less than 41% when the syringe was
filled and capped tightly with its plastic cap. CONCLUSION: The propo
rtion of long-acting gas es escaping in 24 hours from a filled syringe
capped with a stopcock is clinically insignificant.