IN-VITRO ANTIVIRAL ACTIVITY ON DENGUE VIRUS OF MARINE NATURAL-PRODUCTS

Authors
LAILLE M GERALD F DEBITUS C
Citation
M. Laille et al., IN-VITRO ANTIVIRAL ACTIVITY ON DENGUE VIRUS OF MARINE NATURAL-PRODUCTS, Cellular and molecular life sciences, 54(2), 1998, pp. 167-170
Citations number
17
Categorie Soggetti
Biology,"Cell Biology",Biology
Journal title
Cellular and molecular life sciences → ACNP
ISSN journal
1420682X
Volume
54
Issue
2
Year of publication
1998
Pages
167 - 170
Database
ISI
SICI code
1420-682X(1998)54:2<167:IAAODV>2.0.ZU;2-B
Abstract
Metabolites isolated from marine invertebrates, callipeltin A 1, cramb escidin 2, ptilomycalin A 3, celeromycalin 4, gymnochrome B 5, gymnoch rome D 6 and isogymnochrome D 7 previously shown bioactive on either h erpes simplex virus 1 (2, 3, 3) or human immunodeficiency virus (1, 5, 6, 7), were tested on a new in vitro bioassay using the dengue virus 1. Only gymnochrome D and isogymnochrome D isolated from the living fo ssil crinoid Gymnocrinus richeri are highly potent dengue antiviral ag ents.