Background. The first sign in the reported case of superior vena cava
thrombosis secondary to a pacemaker lead, was exceptional: facial flus
h. Case report. A 52-year-old woman had a pacemaker for 10 years for r
hythm disorders. She developed facial flush triggered by exercise and
anteflexion. The clinical examination revealed collateral thoracic cir
culation, suggesting thrombosis of the superior vena cava which was co
nfirmed by the angiocavogram. Discussion. Vasomotor flush is an uncomm
on and misleading initial sign of superior vena cava thrombosis. Induc
tion by exercise and anteflexion is characteristic. Due to the increas
ing number of implanted patients, clinicians should be aware that pace
maker leads are an uncommon cause of superior vena cava thrombosis.