Tc. Li et al., FACTORS AFFECTING THE OUTCOME OF LAPAROSCOPIC OVARIAN DRILLING FOR POLYCYSTIC OVARIAN SYNDROME IN WOMEN WITH ANOVULATORY INFERTILITY, British journal of obstetrics and gynaecology, 105(3), 1998, pp. 338-344
Objective To describe and analyse the factors affecting the pregnancy
rate of laparoscopic ovarian drilling for polycystic ovarian syndrome
in women with anovulatory infertility. Design A retrospective study. S
etting A specialist infertility clinic based at a teaching hospital in
England. Population One hundred and eighteen women, for whom hospital
records and follow up data were available, with polycystic ovarian sy
ndrome who underwent laparoscopic ovarian surgery for anovulatory infe
rtility over a five year period, between January 1991 and December 199
5. Main outcome measures Ovulation and pregnancy rate. Results The cum
ulative conception rate 12 months after the treatment was 54%. Women w
ho conceived following the surgery had a shorter duration of infertili
ty, were treated with diathermy (rather than laser), had higher pre-op
erative luteinising hormone levels, were younger and were more likely
to have ultrasonographic evidence of polycystic ovarian disease. Logis
tic multiple regression analysis showed that the duration of infertili
ty, modality used in treatment (laser or diathermy) and the preoperati
ve levels were the main determinants of the outcome. Conclusion Women
with polycystic ovarian syndrome respond favourably to laparoscopic ov
arian drilling. The success rate in women with infertility duration of
less than three years, treated with diathermy, in whom the pre-operat
ive level was more than 10 IU/L reached 79%.