EFFECT OF N-SUBSTITUTION IN THE FRAGMENTATION MODES OF -DIFLUORO-2,3-DIHYDRO-3-METHYL-4H[1,4]BENZOXAZINES ON ELECTRON-IMPACT

Authors
KANTHARAJ E IYER VS
Citation
E. Kantharaj et Vs. Iyer, EFFECT OF N-SUBSTITUTION IN THE FRAGMENTATION MODES OF -DIFLUORO-2,3-DIHYDRO-3-METHYL-4H[1,4]BENZOXAZINES ON ELECTRON-IMPACT, Indian Journal of Heterocyclic Chemistry, 6(3), 1997, pp. 177-180
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Indian Journal of Heterocyclic Chemistry → ACNP
ISSN journal
09711627
Volume
6
Issue
3
Year of publication
1997
Pages
177 - 180
Database
ISI
SICI code
0971-1627(1997)6:3<177:EONITF>2.0.ZU;2-6
Abstract
The fragmentation process of diagnostic interest in Ofloxacin is the c leavage of 1,4-oxazine ring through beta-hydrogen migration of C-3 hyd rogen to the oxygen resulting in the elimination of CH3-C=CH2 radical to yield the ion d at m/z 276 from the [M-CO2](+) ion.